Acute myeloïde leukemie (AML) incl. Acute promyelocytenleukemie (APL)

…al. PML-RARA kinetics and impact of FLT3-ITD mutations in newly diagnosed acute promyelocytic leukemia treated with ATRA and ATO or ATRA and chemotherapy. Leukemia. 2016:30:1987-1992 Ganzel C, et al. Autologous…

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Acute myeloïde leukemie (AML) incl. Acute promyelocytenleukemie (APL)

…al. PML-RARA kinetics and impact of FLT3-ITD mutations in newly diagnosed acute promyelocytic leukemia treated with ATRA and ATO or ATRA and chemotherapy. Leukemia. 2016:30:1987-1992 Ganzel C, et al. Autologous…

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Multipel myeloom

…et al. Isatuximab Plus Carfilzomib and Dexamethasone Vs Carfilzomib and Dexamethasone in Relapsed/Refractory Multiple Myeloma (IKEMA): Interim Analysis of a Phase 3, Randomized, Open-Label Study. ASH 2020. Abstract 2316. Seigel…

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Verworven aplastische anemie

…stem cell source for sibling transplants in acquired aplastic anemia: survival advantage for bone marrow in all age groups. Haematologica 2012;97:1142-1148. Bacigalupo A et al. Fludarabine, cyclophosphamide and anti-thymocyte globulin…

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Diffuus grootcellig B-cellymfoom (DLBCL)

…survival advantage in patients with double-hit lymphomas: a systematic review and meta-analysis. Br J Haematol 2015;170(4):504-14. Dunleavy K, Fanale MA, Abramson JS, et al. Dose-adjusted EPOCH-R (etoposide, prednisone, vincristine, cyclophosphamide,…

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Systemische mastocytose

…combinatie met prednisolon (ca. 45-60% SM-AHN, resp. ISM en ASM). Dosering: opbouwen naar max. 90-135 µg/week subcutaan (conform onderstaand schema) Co-medicatie: prednisolon (conform onderstaand schema) Aandachtspunten: langzaam werkingsmechanisme, depressie en…

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Acute lymfatische leukemie en lymfoblastair lymfoom

…for Advanced Acute Lymphoblastic Leukemia. N Engl J Med. 2017;376:836-847 Lepretre S, Touzart A, Vermeulin T, et al. Pediatric-Like Acute Lymphoblastic Leukemia Therapy in Adults With Lymphoblastic Lymphoma: The GRAALL-LYSA…

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Amyloïdose

…voor ASCT: NEOD001 studie (AFFRIM-AL): stadium IV AL-Amyloïdose: (Dara)-CyBorD +/- Birtamimab (=monoklonale antistof tegen amyloid) CAEL 101: 301 en 302 ; stadium IIIA resp. III B AL Amyloïdose: (Dara)-CyBorD +/-…

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Porfyrieën

…Overerveringspatroon X-gebonden protoporfyrie ALAS2 Cutaan X-chromosoom gebonden ADP = ALAD-deficiëntie-porfyrie ALA-dehydratase (ALAD) Acuut Autosomaal recessief AIP = Acute intermitterende porfyrie PBG-deaminase (PBGD) Acuut Autosomaal dominant CEP = Congenitale erytropoëtische porfyrie…

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Patiëntenverenigingen

AIHA, aplastische anemie (AA) en PNH Platform Stichting Zeldzame Bloedziekten biedt informatie over: HX, CDA, HES, TTP, AIHA, DBA, HS, PKD, HE en HPP Stichting Zeldzame Bloedziekten (SZB) Tel. (06)…

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